Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952346 | 1.00 | MEN1 (0.51) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL7718173 | 0.89 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL2211809 | 0.89 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL12643955 | 0.89 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL391537 | 0.89 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL3445777 | 0.89 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL10241524 | 0.89 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28881882 | 0.87 | MEN1 (0.63) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL20143076 | 0.87 | MEN1 (0.55) | MEN1GAAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28881885 | 0.87 | MEN1 (0.63) | MEN1GAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |