SCHEMBL2211809

SCHEMBL2211809

CC(=O)NCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.58
MEN1 O00255 1/20 0.54
GAA P10253 1/20 0.54
KMT2A Q03164 1/20 0.54
CTSK P43235 8/20 0.50
CTSS P25774 5/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
CAPN1 P07384 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
TGM2 P21980 1/20 0.44
SIRT5 Q9NXA8 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12643955 1.00 FOLH1 (0.58) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL7718173 1.00 FOLH1 (0.58) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL1373885 0.96 MEN1 (0.59) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL1373880 0.96 MEN1 (0.59) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL391537 0.91 MEN1 (0.65) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL10241524 0.91 MEN1 (0.65) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL3445777 0.91 MEN1 (0.65) FOLH1MEN1GAAKMT2ACTSK
Hydrochloric Acid SCHEMBL28881882 0.90 MEN1 (0.63) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL21702752 0.90 MEN1 (0.63) FOLH1MEN1GAAKMT2ACTSK
SCHEMBL20143076 0.90 MEN1 (0.55) FOLH1MEN1GAAKMT2ACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120114563-A Biotin tripeptide with hair growth function and composition, preparation method and application thereof 天津科技大学 2025-06-10 CN claimed
CN-116253770-B Gemcitabine prodrug with double activation of HDAC and CTSL as well as preparation method and application thereof 山东省科学院生物研究所 2024-12-17 CN claimed
CN-117800910-A Double-lock An Nai Pht anticancer prodrug AcKLP and preparation method and application thereof 南京师范大学 2024-04-02 CN claimed
CN-116253770-A Gemcitabine prodrug with double activation of HDAC and CTSL as well as preparation method and application thereof 山东省科学院生物研究所 2023-06-13 CN claimed
CN-113041361-B Diagnosis and treatment integrated material responding to HDAC and CTSL and preparation method and application thereof 广州市第一人民医院(广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院) 2022-08-16 CN claimed
CN-116583303-B Tripterine conjugates and uses thereof 瑞阳公司 2026-05-12 CN disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20250339542-A1 CONVERSION OF A BIOLOGICALLY SILENT MIRNA BINDING SMALL MOLECULE TO AN MIRNA DEGRADER UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-11-06 US disclosed
US-20250304645-A1 Prodrugs of GLP-1 Polypeptide and Uses Thereof NOVO NORDISK A/S (DK) 2025-10-02 US disclosed
CN-120114563-A Biotin tripeptide with hair growth function and composition, preparation method and application thereof 天津科技大学 2025-06-10 CN disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
EP-4522220-A1 PRODRUGS OF GLP-1 POLYPEPTIDE AND USES THEREOF Novo Nordisk A/S (DK) 2025-03-19 EP disclosed
EP-1389616-B1 3,4-Dihalobenzylpiperidine derivatives and their medical use MITSUBISHI TANABE PHARMA CORP (JP) 2011-07-27 EP disclosed
US-20110082208-A1 THERAPIES FOR CANCER USING ISOTOPICALLY SUBSTITUTED LYSINE BIOJIVA LLC 2011-04-07 US disclosed
US-7115635-B2 Benzylpiperidine compound MITSUBISHI PHARMA CORPORATION (JP) 2006-10-03 US disclosed
US-20040158071-A1 Chemokine inhibitors and stability in blood MITSUBISHI PHARMA CORPORATION (JP) 2004-08-12 US disclosed
EP-1389616-A1 NOVEL BENZYLPIPERIDINE COMPOUND Mitsubishi Pharma Corporation (JP) 2004-02-18 EP disclosed
US-6127341-A AMINOMETHYL-N-(1-((2-(2-THIENYL)-1-(1-CARBAMOYL-5 -AMINOPENTYLCARBAMOYL)ETHYL)-N-METHYLCARBAMOYL)-2-(2 -NAPTHYL)ETHYL)BENZAMIDE, FOR EXAMPLE; ADMINISTERING TO STIMULATE GROWTH, MILK OR WOOL PRODUCTION IN ANIMALS NOVO NORDISK A/S (DK) 2000-10-03 US disclosed
EP-1005484-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 2000-06-07 EP disclosed
WO-1998058950-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110082208-A1 THERAPIES FOR CANCER USING ISOTOPICALLY SUBSTITUTED LYSINE AADAT, DOT1L, TP53 FOLH1 7/4885MEN1 1390/4885GAA 1146/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 FOLH1 2368/4885MEN1 4664/4885GAA 2026/4885
US-20250339542-A1 CONVERSION OF A BIOLOGICALLY SILENT MIRNA BINDING SMALL MOLECULE TO AN MIRNA DEGRADER NSUN3, AGO2, ZFR FOLH1 1779/4885MEN1 1716/4885GAA 849/4885
US-20040158071-A1 Chemokine inhibitors and stability in blood CCL2, CXCR1, CCR5 FOLH1 918/4885MEN1 3525/4885GAA 3114/4885
US-20250304645-A1 Prodrugs of GLP-1 Polypeptide and Uses Thereof GLP1R, IAPP, GCG FOLH1 56/4885MEN1 480/4885GAA 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.