Dimethylamine

Dimethylamine

SCHEMBL3953015

C=CCNC(=O)C(=C)C.CNC

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 1/20 0.43
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 1/20 0.41
FAAH O00519 1/20 0.40
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 5/20 0.37
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TGFBR1 P36897 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30604 0.96
Ammonia Solution, Strong SCHEMBL1326687 0.93 TSHR (0.45) TSHRSMN1; SMN2MAPTKDM4EKMT2A
Ammonia Solution, Strong SCHEMBL9663785 0.93 TSHR (0.45) TSHRSMN1; SMN2MAPTKDM4EKMT2A
Hydrochloric Acid SCHEMBL10610285 0.93 TSHR (0.45) TSHRSMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL8032280 0.89 TSHR (0.42) TSHRSMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL4843584 0.86 TSHR (0.45) TSHRSMN1; SMN2MAPTKDM4EKMT2A
Ammonia Solution, Strong SCHEMBL29236362 0.80 KDM4E (0.35) TSHRSMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL28018915 0.80 KDM4E (0.35) TSHRSMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL28196153 0.80 FAAH (0.37) TSHRSMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL8244987 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009532563-A 2009-09-10 JP claimed
EP-2010239-A2 WATER RESISTANT FILM FORMING COMPOSITIONS INCORPORATING HYDROPHILIC ACTIVITIES Symyx Technologies, Inc. (US) 2009-01-07 EP claimed
WO-2007123789-A2 WATER RESISTANT FILM FORMING COMPOSITIONS INCORPORATING HYDROPHILIC ACTIVITIES SYMYX TECHNOLOGIES, INC. (US) 2007-11-01 WO claimed
US-20070238807-A1 Water resistant film forming compositions incorporating hydrophilic activities SYMYX SOLUTIONS, INC. 2007-10-11 US claimed
US-20070238807-A1 Water resistant film forming compositions incorporating hydrophilic activities SYMYX SOLUTIONS, INC. 2007-10-11 US disclosed