SCHEMBL395316

SCHEMBL395316

C=C[Si](C)(C)O[Si](CCCOC(=O)C(=C)C)(O[Si](C)(C)C=C)O[Si](C)(C)C=C

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
THRB P10828 1/20 0.40
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476340 0.95 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5068000 0.93 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5701671 0.93 TSHR (0.43) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15483421 0.91 TSHR (0.39) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5702056 0.90 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15483422 0.90 TSHR (0.38) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3477369 0.88 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3478200 0.88 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5701562 0.87 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25924848 0.85 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4135623-B1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT INC (US) 2026-04-08 EP claimed
US-20250163346-A1 TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2025-05-22 US claimed
US-12215299-B2 Treatment compositions THE PROCTER & GAMBLE COMPANY (US) 2025-02-04 US claimed
US-20240252311-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. 2024-08-01 US claimed
CN-117025120-A Acrylic OCA optical cement with double-layer structure and preparation method thereof 深圳市高仁电子新材料有限公司 2023-11-10 CN claimed
US-20230242842-A1 TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2023-08-03 US claimed
WO-2023078367-A1 SECONDARY BATTERY 珠海冠宇电池股份有限公司 2023-05-11 WO claimed
US-11643618-B2 Treatment compositions THE PROCTER & GAMBLE COMPANY (US) 2023-05-09 US claimed
EP-4135623-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RxSight, Inc. (US) 2023-02-22 EP claimed
CN-112375176-B High oxygen permeable silica hydrogel formula and preparation method of high oxygen permeable silica hydrogel corneal contact lens 甘肃康视达科技集团有限公司 2023-02-10 CN claimed
US-20090210002-A1 METHOD OF FORMING A CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES LLP (US) 2009-08-20 US claimed
EP-1945231-A2 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL Salamone, Ann Beal (US) 2008-07-23 EP claimed
WO-2007022377-A2 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL SALAMONE ANN BEAL (US) 2007-02-22 WO claimed
US-20070041935-A1 Polymerizable cyanoacrylate monomer and volatile liquid selected from linear and cyclic siloxanes, polydimethylsiloxanes, isooctane, and octane; kits ROCHAL PARTNERS LLP 2007-02-22 US claimed
EP-1401634-B1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE ESSILOR INT (FR) 2006-10-04 EP claimed
US-6986857-B2 Method for preparing a mold part useful for transferring a coating onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2006-01-17 US claimed
EP-1588829-A2 Method for preparing a mold part useful for transfering a coating onto an optical substrate ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2005-10-26 EP claimed
US-20040065968-A1 Method for preparing a mold part useful for transferring a coating onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2004-04-08 US claimed
EP-1312659-A1 ADHESIVE COMPOSITION AND OPTICAL DEVICE USING THE SAME Nippon Sheet Glass Co., Ltd. (JP) 2003-05-21 EP claimed
US-20020074086-A1 Adhesive composition and optical device using the same NIPPON SHEET GLASS CO., LTD. (JP) 2002-06-20 US claimed