Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395316 | 0.95 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5068000 | 0.89 | TSHR (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5701671 | 0.89 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3478409 | 0.88 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3476983 | 0.88 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15483421 | 0.87 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5702056 | 0.86 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15483422 | 0.86 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL397519 | 0.84 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3477369 | 0.84 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4135623-B1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER | RXSIGHT INC (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260069403-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE | RXSIGHT, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-20240252311-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER | RXSIGHT, INC. | 2024-08-01 | — | — | US | disclosed |
| EP-4294325-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE | RxSight, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| CN-116867464-A | Composite optically tunable intraocular lens with diffractive structure | RX视觉股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4135623-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER | RxSight, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-115397365-A | Composite light adjustable intraocular lens with adhesion promoter | RX视觉股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022177821-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE | RXSIGHT, INC. (US) | 2022-08-25 | — | — | WO | disclosed |
| US-20210322152-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER | RXSIGHT, INC. (US) | 2021-10-21 | — | — | US | disclosed |
| WO-2021211888-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER | RXSIGHT, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20210251744-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE | RXSIGHT, INC. (US) | 2021-08-19 | — | — | US | disclosed |
| EP-2396355-B1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN INC (US) | 2018-05-23 | — | — | EP | disclosed |
| US-8680172-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130245756-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | LILLY MING INTERNATIONAL, INC. | 2013-09-19 | — | — | US | disclosed |
| US-8430928-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120245684-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2012-09-27 | — | — | US | disclosed |
| US-8222360-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20100211170-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010093823-A2 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260069403-A1 | COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE | IGLV6-57, SMCHD1, UACA | TSHR 819/4885THRB 577/4885POLB 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.