SCHEMBL395328

SCHEMBL395328

C=CC(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](CCCOC(=O)C=C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.39
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331043 0.98 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8467147 0.93 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
Acrylamide SCHEMBL29899654 0.92 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14278964 0.92 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10661647 0.92 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5838718 0.92 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL31290834 0.91 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5838048 0.90 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL393548 0.90 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL15215482 0.90 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150252125-A1 CURABLE RESIN COMPOSITIONS AND BARRIER STACKS INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2015-09-10 US claimed
US-20150252125-A1 CURABLE RESIN COMPOSITIONS AND BARRIER STACKS INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2015-09-10 US disclosed
US-20150252125-A1 CURABLE RESIN COMPOSITIONS AND BARRIER STACKS INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2015-09-10 US disclosed
US-20150252125-A1 CURABLE RESIN COMPOSITIONS AND BARRIER STACKS INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2015-09-10 US disclosed
US-8110697-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-02-07 US disclosed
US-8101789-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-01-24 US disclosed
EP-1499692-B1 SUBSTRATES HAVING A BIOFILM-INHIBITING COATING LEIBNIZ INST NEUE MATERIALIEN (DE) 2011-08-10 EP disclosed
US-7799432-B2 Comprised of inorganic condensate modified with acrylatedsiloxane crosslinked polymer having fluorine functionality and copper or silver salt colloids; antimicrobial agents; adherence to all types of surface materials LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) 2010-09-21 US disclosed
EP-2125833-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
EP-2125834-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
US-20100041909-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-18 US disclosed
US-20100029972-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-04 US disclosed
EP-1500302-B1 HEARING AID OR HEARING AID PARTS FOR INSERTING INTO THE AUDITORY CANAL AND/OR THE AURICLE OF A WEARER AUDIO SERVICE GMBH AS (DE) 2006-05-03 EP disclosed
US-20050159504-A1 Substrates having a biofilm-inhibiting coating INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) 2005-07-21 US disclosed
US-6855371-B2 Method for producing a microstructured surface relief by embossing thixotropic layers INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) 2005-02-15 US disclosed
EP-1086162-B1 NANOSTRUCTURED FORMS AND LAYERS AND METHOD FOR PRODUCING THEM USING STABLE WATER-SOLUBLE PRECURSORS INST NEUE MAT GEMEIN GMBH (DE) 2004-11-10 EP disclosed
EP-1248685-B1 METHOD FOR PRODUCING A MICROSTRUCTURED SURFACE RELIEF BY EMBOSSING THIXOTROPIC LAYERS AND MICROSTRUCTURED SURFACE RELIEF INST NEUE MAT GEMEIN GMBH (DE) 2004-09-08 EP disclosed
EP-1060223-B1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INST NEUE MAT GEMEIN GMBH (DE) 2004-08-18 EP disclosed
US-20040026832-A1 Method for producing a microstructured surface relief by embossing thixotropic layers LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) 2004-02-12 US disclosed
US-6620514-B1 Contacting an aqueous and/or alcoholic sol of a compound of an element selected from silicons and metals with species possessing hydrolysable alkoxy groups and comprising at least one organically modified alkoxysilane; alcohol removed INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) 2003-09-16 US disclosed