Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331043 | 0.92 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL395328 | 0.90 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7715703 | 0.90 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL71730 | 0.90 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5070566 | 0.89 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5701331 | 0.89 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Methane SCHEMBL28113061 | 0.88 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Ethylene SCHEMBL22126280 | 0.88 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28208777 | 0.88 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL441818 | 0.88 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604658-B2 | Organic silicon compound, surface treatment agent containing same, resin composition containing same, and gel or cured product of same | DOW TORAY CO., LTD. (JP) | 2020-03-31 | — | — | US | disclosed |
| WO-2015022998-A1 | NOVEL ORGANIC SILICON COMPOUND, SURFACE TREATMENT AGENT CONTAINING SAME, RESIN COMPOSITION CONTAINING SAME, AND GEL OR CURED PRODUCT OF SAME | DOW CORNING TORAY CO., LTD. (JP) | 2015-02-19 | — | — | WO | disclosed |
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-2125833-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2125834-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604658-B2 | Organic silicon compound, surface treatment agent containing same, resin composition containing same, and gel or cured product of same | ASH2L, RPS7, MRPS27 | TSHR 3888/4885ALDH1A1 3826/4885CYP3A4 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.