SCHEMBL39539

SCHEMBL39539

COC(=O)CCCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272758 0.93 LMNA (0.64)
SCHEMBL436881 0.91 LMNA (0.68)
SCHEMBL7201423 0.91 LMNA (0.68)
SCHEMBL415770 0.91 LMNA (0.68)
SCHEMBL8811913 0.91 LMNA (0.68)
SCHEMBL1976573 0.91 LMNA (0.68)
SCHEMBL8814164 0.91 LMNA (0.68)
SCHEMBL8812283 0.91 LMNA (0.68)
SCHEMBL8441499 0.91 LMNA (0.68)
SCHEMBL274488 0.91 LMNA (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107904-B1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE INC (US) 2019-06-05 EP claimed
EP-3488000-A1 METHODS AND MATERIALS FOR BIOSYNTHESIZING MULTIFUNCTIONAL, MULTIVARIATE MOLECULES VIA CARBON CHAIN MODIFICATION INVISTA Textiles (U.K.) Limited (GB) 2019-05-29 EP claimed
US-20180273987-A1 METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS INVISTA NORTH AMERICA S.A.R.L. (US) 2018-09-27 US claimed
US-10011582-B2 Substituted delta-lactones and methods of preparing same P2 SCIENCE, INC. (US) 2018-07-03 US claimed
US-9938543-B2 Methods, reagents and cells for biosynthesizing glutarate methyl ester INVISTA NORTH AMERICA S.A.R.L. (US) 2018-04-10 US claimed
CN-107876092-A The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate 华东理工大学 2018-04-06 CN claimed
US-9920339-B2 Methods, reagents and cells for biosynthesizing compounds INVISTA NORTH AMERICA S.A.R.L. (US) 2018-03-20 US claimed
WO-2018022633-A1 METHODS AND MATERIALS FOR BIOSYNTHESIZING MULTIFUNCTIONAL, MULTIVARIATE MOLECULES VIA CARBON CHAIN MODIFICATION INVISTA TEXTILES (U.K.) LIMITED (GB) 2018-02-01 WO claimed
US-20180023103-A1 METHODS AND MATERIALS FOR BIOSYNTHESIZING MULTIFUNCTIONAL, MULTIVARIATE MOLECULES VIA CARBON CHAIN MODIFICATION INVISTA NORTH AMERICA S.A.R.L. 2018-01-25 US claimed
CN-107417719-A A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate 华东理工大学 2017-12-01 CN claimed
EP-1506175-A1 N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2005-02-16 EP claimed
US-20040082639-A1 N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders JANSSEN PHARMACEUTICA, N.V. (BE) 2004-04-29 US claimed
WO-2003097609-A1 N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2003-11-27 WO claimed
US-5811389-A INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS HOFFMANN-LA ROCHE INC. (US) 1998-09-22 US claimed
EP-0460883-B1 Process for beta-hydroxy-alpha-amino acids UNIV NOTRE DAME DU LAC (US) 1997-01-15 EP claimed
CN-1086825-A Three ring and tetracyclic compounds HOFFMANN LA ROCHE (CH) 1994-05-18 CN claimed
EP-0592791-A2 Tricyclic compounds and peptide derivatives thereof F. HOFFMANN-LA ROCHE AG (CH) 1994-04-20 EP claimed
EP-0460883-A2 Process for beta-hydroxy-alpha-amino acids THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1991-12-11 EP claimed
EP-0036663-B1 OXIRANEBUTANOIC ACID DERIVATIVES, THEIR PREPARATION AND USE, AND MEDICAMENTS CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-09-12 EP claimed
US-4401660-A TYLOSINS; VETERINARY MEDICINE; PASTEURELLA; ANIMAL GROWTH REGULATORS ELI LILLY AND COMPANY (US) 1983-08-30 US claimed