Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305149 | 0.97 | MEN1 (0.82) | MEN1TP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2202342 | 0.97 | MEN1 (0.82) | MEN1TP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30677423 | 0.95 | MEN1 (0.95) | MEN1TP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27794130 | 0.92 | MEN1 (0.82) | MEN1TP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2899860 | 0.92 | MEN1 (0.80) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL28000052 | 0.89 | MEN1 (0.76) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11741744 | 0.89 | MEN1 (0.85) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL27660773 | 0.89 | MEN1 (0.76) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2678907 | 0.84 | KMT2A (0.83) | MEN1TP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6040035 | 0.84 | MEN1 (0.62) | MEN1TP53KMT2ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960595-B2 | 5-6 to 5-7 Heterobicycles as factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-11-01 | — | — | US | claimed |
| US-8524898-B2 | Proton acceptor iminium/carbocation-type coupling agents | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| WO-2009138985-A2 | COUPLING AGENTS FOR THE SYNTHESIS OF POLYPEPTIDES AND POLYNUCLEOTIDES | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2009-11-19 | — | — | WO | disclosed |
| EP-2051974-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008139481-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | PHAX, GIPR, IAPP | MEN1 882/4885TP53 4069/4885KMT2A 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.