Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CHKA | P35790 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202342 | 1.00 | MEN1 (0.82) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL3954355 | 0.97 | MEN1 (0.86) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL30677423 | 0.92 | MEN1 (0.95) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL27794130 | 0.90 | MEN1 (0.82) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2899860 | 0.89 | MEN1 (0.80) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL28000052 | 0.87 | MEN1 (0.76) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL11741744 | 0.87 | MEN1 (0.85) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL27660773 | 0.87 | MEN1 (0.76) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL8674256 | 0.85 | MEN1 (0.60) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2323473 | 0.84 | ALDH1A1 (0.93) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. | 2009-10-29 | — | — | US | disclosed |
| US-7186710-B2 | Phthalazinones | ALTANA PHARMA AG (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20040127707-A1 | PDE4/7 inhibitors useful in treatment of airway disorders, autoimmune system disorders, skin disorders, arthritis, nerve system disorders | ALTANA PHARMA AG (DE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127707-A1 | PDE4/7 inhibitors useful in treatment of airway disorders, autoimmune system disorders, skin disorders, arthritis, nerve system disorders | PDE4A, PDE4B, PDE7B | MEN1 2426/4885KMT2A 3900/4885TP53 4268/4885 |
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | IL2, IL4I1, IFNG | MEN1 2721/4885KMT2A 3187/4885TP53 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.