Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143065 | 0.83 | PRSS1 (0.69) | PRSS1PRSS3PRSS2F12LMNA | |
| SCHEMBL8404520 | 0.82 | PRSS1 (1.00) | PRSS1PRSS3PRSS2F12LMNA | |
| Hydrochloric Acid SCHEMBL5118627 | 0.80 | PRSS1 (0.95) | PRSS1PRSS3PRSS2F12LMNA | |
| SCHEMBL9314470 | 0.79 | LMNA (0.54) | PRSS1PRSS3PRSS2F12LMNA | |
| SCHEMBL23592021 | 0.78 | TSHR (0.50) | PRSS1PRSS3PRSS2TSHRCASP1 | |
| SCHEMBL1805871 | 0.78 | LCK (0.53) | PRSS1PRSS3PRSS2TSHRCASP1 | |
| Hydrochloric Acid SCHEMBL4280302 | 0.77 | LMNA (0.52) | PRSS1PRSS3PRSS2F12LMNA | |
| SCHEMBL12834788 | 0.77 | PRSS1 (0.67) | PRSS1PRSS3PRSS2F12LMNA | |
| SCHEMBL8307718 | 0.77 | PRSS1 (0.67) | PRSS1PRSS3PRSS2F12LMNA | |
| SCHEMBL1232136 | 0.77 | PRSS1 (0.67) | PRSS1PRSS3PRSS2F12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | disclosed |
| US-8101637-B2 | Alkynyl derivatives as modulators of metatropic glutamate receptors | ADDEX PHARMA SA (CH) | 2012-01-24 | — | — | US | disclosed |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | GRM5, GRM2, GRM1 | PRSS1 4372/4885PRSS3 4706/4885PRSS2 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.