SCHEMBL3955434

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3959106	0.93	ENPP2 (0.50)	MAPTENPP2KDM4ENPC1POLB
	SCHEMBL3953186	0.88	MAPT (0.59)	MAPTAGTR1AGTR2KDM4ETDP1
	SCHEMBL3961340	0.88	MAPT (0.53)	MAPTAGTR1AGTR2KDM4ETDP1
	SCHEMBL3964209	0.88	ENPP2 (0.55)	MAPTENPP2KDM4ETDP1NPC1
	SCHEMBL3965629	0.87	MAPT (0.50)	MAPTENPP2AGTR1AGTR2KDM4E
	SCHEMBL3955412	0.86	MAPT (0.49)	MAPTENPP2AGTR1AGTR2KDM4E
	SCHEMBL3959990	0.86	MAPT (0.51)	MAPTAGTR1AGTR2KDM4ETDP1
	SCHEMBL5129012	0.86	MAPT (0.53)	MAPTAGTR1AGTR2KDM4ETDP1
	SCHEMBL3955336	0.86	ENPP2 (0.48)	MAPTENPP2KDM4ENPC1POLB
	SCHEMBL3963686	0.85	MAPT (0.51)	MAPTENPP2AGTR1AGTR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.