Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956212 | 1.00 | NOTUM (0.43) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL5995411 | 0.81 | NOTUM (0.33) | NOTUMBRD4 | |
| SCHEMBL3956526 | 0.79 | NOTUM (0.59) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL3956544 | 0.79 | NOTUM (0.59) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL3956520 | 0.79 | NOTUM (0.59) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL7220138 | 0.73 | NOTUM (0.43) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL7216052 | 0.71 | NOTUM (0.56) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL7214657 | 0.69 | NOTUM (0.45) | NOTUMBRD4HTR1ADRD2HTR2A | |
| SCHEMBL5993470 | 0.69 | NOTUM (0.33) | NOTUMBRD4ALDH1A1HTT | |
| SCHEMBL3956205 | 0.68 | NOTUM (0.41) | NOTUMBRD4HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544685-B2 | 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043058-A1 | Novel 2,3-dihydroindole compounds | HTR2C, HTR2A, HTR5A | NOTUM 4483/4885BRD4 907/4885HTR1A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.