Butyl Fumarate

Butyl Fumarate

SCHEMBL3956264

C=CC(=O)OCCCC.C=Cc1ccccc1.CCCCOC(=O)/C=C\C(=O)O

nearest known ligand 0.61

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.61
TSHR P16473 3/20 0.56
HPGD P15428 1/20 0.56
ATM Q13315 1/20 0.51
THRB P10828 1/20 0.46
APP P05067 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP3A4 P08684 1/20 0.41
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyl Fumarate SCHEMBL3956267 1.00 HCAR2 (0.61) HCAR2TSHRHPGDATMTHRB
Styrene SCHEMBL5698366 0.97 TSHR (0.59) HCAR2TSHRHPGDATMTHRB
Styrene SCHEMBL5698364 0.97 TSHR (0.59) HCAR2TSHRHPGDATMTHRB
Butyl Fumarate SCHEMBL10908635 0.96 HCAR2 (0.57) HCAR2TSHRHPGDATMTHRB
Ethyl Fumarate SCHEMBL250119 0.96 HCAR2 (0.57) HCAR2TSHRHPGDATMTHRB
Butyl Fumarate SCHEMBL2164919 0.96 HCAR2 (0.67) HCAR2TSHRHPGDATMAPP
Butyl Fumarate SCHEMBL2164913 0.96 HCAR2 (0.67) HCAR2TSHRHPGDATMAPP
Styrene SCHEMBL8094670 0.92 HCAR2 (0.58) HCAR2TSHRHPGDTHRBAPP
Styrene SCHEMBL8094673 0.92 HCAR2 (0.58) HCAR2TSHRHPGDTHRBAPP
Styrene SCHEMBL5832170 0.92 HCAR2 (0.52) HCAR2TSHRHPGDATMTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1548509-B1 Process for producing toner, and apparatus for modifying surfaces of toner particles CANON KK (JP) 2009-06-17 EP disclosed
US-7506830-B2 Apparatus for modifying surfaces of toner particles CANON KABUSHIKI KAISHA (JP) 2009-03-24 US disclosed
US-20080149535-A1 APPARATUS FOR MODIFYING SURFACES OF TONER PARTICLES CANON KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed
EP-1091257-B1 Process for producing toner CANON KK (JP) 2008-05-14 EP disclosed
EP-1081935-B1 Electrophotographic apparatus with reduced fog and improved cleaning CANON KK (JP) 2008-04-09 EP disclosed
US-7273686-B2 Mixture of toner, binder and magnetic material CANON KABUSHIKI KAISHA (JP) 2007-09-25 US disclosed
EP-1035449-B1 Toner CANON KK (JP) 2007-08-08 EP disclosed
EP-1772777-A1 Toner, process for producing toner, image forming method and apparatus unit CANON KABUSHIKI KAISHA (JP) 2007-04-11 EP disclosed
US-7060406-B2 Light-receiving member having a surface roughness Ra of from 15 nm to 100 nm. CANON KABUSHIKI KAISHA (JP) 2006-06-13 US disclosed
EP-1286225-B1 Developing assembly, process cartridge and image-forming method CANON KK (JP) 2005-11-09 EP disclosed
US-5210617-A Developer for developing electrostatic images and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1993-05-11 US disclosed
US-5139914-A Toner and negatively chargeable spherical resin particles, high quality images without causing toner sticking CANON KABUSHIKI KAISHA (JP) 1992-08-18 US disclosed
US-5084369-A Binder resins with toners for electron photography and electrostatic recording and printing CANON KABUSHIKI KAISHA (JP) 1992-01-28 US disclosed
EP-0410483-A1 Developer for developing electrostatic images and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-01-30 EP disclosed
EP-0387769-A1 Toner containing a diarylguanidine type compound for developing electrostatic images CANON KABUSHIKI KAISHA (JP) 1990-09-19 EP disclosed
US-4906548-A Developer for developing electrostatic latent image and image forming method CANON KABUSHIKI KAISHA (JP) 1990-03-06 US disclosed
US-4886725-A Toner composition containing organotin oxide CANON KABUSHIKI KAISHA (JP) 1989-12-12 US disclosed
US-4868084-A TREATED SILICA POWDER, HYDROPHOBIC, NEGATIVELY CHARGEABLE CANON KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
US-4657838-A DEVELOPMENT OF ELECTROSTATIC IMAGES CANON KABUSHIKI KAISHA (JP) 1987-04-14 US disclosed
US-4336318-A ADJUSTING THE THICKNESS OF TONE LAYER TO PRODUCE FOG FREE IMAGES CANON KABUSHIKI KAISHA (JP) 1982-06-22 US disclosed