Hydrochloric Acid

Hydrochloric Acid

SCHEMBL395628

CC1=Cc2c(ccc3ccccc23)C1[Ti+2](C1C(C)=Cc2c1ccc1ccccc21)=[Si](C)C.[Cl-].[Cl-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.30
SLC6A3 known ✓ Q01959 1/20 0.30
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 4/20 0.34
CYP2A6 P11509 4/20 0.34
TSHR P16473 3/20 0.33
CYP1A2 P05177 2/20 0.33
HSD17B10 Q99714 4/20 0.32
HPGD P15428 3/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
KDM1A O60341 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
SLC6A4 P31645 2/20 0.31
CYP3A4 P08684 2/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
RAB9A P51151 1/20 0.30
CASP7 P55210 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2535528 0.86 KDM1A (0.32) KDM4EALDH1A1CYP2A6HPGDMAPT
Hydrochloric Acid SCHEMBL5613031 0.82 KDM4E (0.40) KDM4EALDH1A1CYP1A2SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL819655 0.79 KDM4E (0.34) KDM4EALDH1A1CYP2A6TSHRCYP1A2
Hydrochloric Acid SCHEMBL2536471 0.78
Hydrochloric Acid SCHEMBL2539854 0.78 GSTP1 (0.35) SLC6A4SLC6A2SLC6A3
Hydrochloric Acid SCHEMBL397901 0.75 PDCD1 (0.31)
Hydrochloric Acid SCHEMBL967172 0.75 PDCD1 (0.31)
Hydrochloric Acid SCHEMBL2534387 0.75
Hydrochloric Acid SCHEMBL5689511 0.73 KDM4E (0.37) KDM4EALDH1A1CYP2A6TSHRCYP1A2
Hydrochloric Acid SCHEMBL4464917 0.73 KDM4E (0.37) KDM4EALDH1A1CYP2A6TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3130635-B1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT SUMITOMO CHEMICAL CO (JP) 2020-02-26 EP disclosed
US-9909002-B2 Resin composition, cross-linked product, and method for manufacturing cross-linked product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-06 US disclosed
US-20170121516-A1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-04 US disclosed
EP-3130635-A1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT Sumitomo Chemical Company Limited (JP) 2017-02-15 EP disclosed
US-9200093-B2 Polymerization method using surfactant-containing particle SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-01 US disclosed
US-20140288251-A1 POLYMERIZATION METHOD USING SURFACTANT-CONTAINING PARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-25 US disclosed
WO-2013085074-A1 POLYMERIZATION METHOD USING SURFACTANT-CONTAINING PARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-13 WO disclosed
US-8431659-B2 Prepolymerized catalyst for olefin polymerization, method of producing this prepolymerized catalyst and method of producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-30 US disclosed
EP-1880986-B1 PROCESS FOR PRODUCING SATURATED ALIPHATIC HYDROCARBONS, AND LUBRICANT COMPOSITIONS THEREOF IDEMITSU KOSAN CO (JP) 2013-03-06 EP disclosed
US-8373011-B2 Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-20030069127-A1 Modified particle,support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMTED (JP) 2003-04-10 US disclosed
EP-1275662-A1 MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-15 EP disclosed
US-20020143124-A1 Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-03 US disclosed
EP-1153947-A1 OLEFIN COPOLYMER, FILM, AND SHEET IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-11-14 EP disclosed
US-6316557-B1 FOR PRODUCING HIGH QUALITY, STEREOSPECIFIC POLYOLEFINS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-11-13 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-0985673-A2 Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-15 EP disclosed
EP-0984016-A1 ALUMINUM COMPOUND AND PROCESS FOR PRODUCING THE SAME, CATALYST FOR OLEFIN POLYMER PRODUCTION, AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-03-08 EP disclosed
EP-0945471-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-09-29 EP disclosed