Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960123 | 0.91 | PPARA (0.42) | PPARAPPARGL3MBTL1MAPTTHRB | |
| SCHEMBL3763324 | 0.90 | PPARA (0.48) | PPARAPPARGL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3759904 | 0.87 | PPARA (0.50) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3759907 | 0.87 | PPARA (0.50) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3763027 | 0.84 | PPARA (0.39) | PPARAPPARGALDH1A1PSEN1PSEN2 | |
| SCHEMBL3769310 | 0.83 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL3776262 | 0.82 | PPARA (0.39) | PPARAPPARGALDH1A1PSEN1PSEN2 | |
| SCHEMBL5448514 | 0.81 | PPARA (0.44) | PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL3758770 | 0.81 | PPARA (0.42) | PPARAPPARGALDH1A1 | |
| SCHEMBL3762603 | 0.81 | PPARA (0.39) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |