Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.42 |
| ▸ | PPARG | P37231 | 13/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956356 | 0.91 | PPARA (0.43) | PPARAPPARGMAPTTHRBL3MBTL1 | |
| SCHEMBL3764480 | 0.90 | PPARA (0.46) | PPARAPPARGS1PR1 | |
| SCHEMBL3762811 | 0.86 | PPARA (0.49) | PPARAPPARGMAPTTHRBL3MBTL1 | |
| SCHEMBL3762808 | 0.86 | PPARA (0.49) | PPARAPPARGMAPTTHRBL3MBTL1 | |
| SCHEMBL3769310 | 0.84 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL3759960 | 0.83 | PPARA (0.49) | PPARAPPARGMAPTRXRARXRB | |
| SCHEMBL3768056 | 0.83 | PPARA (0.48) | PPARAPPARGMAPTRXRARXRB | |
| SCHEMBL3762603 | 0.82 | PPARA (0.39) | PPARAPPARGS1PR1 | |
| SCHEMBL3758105 | 0.82 | PPARA (0.38) | PPARAPPARGS1PR1 | |
| SCHEMBL3769108 | 0.82 | NPC1 (0.41) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |