Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18986703 | 0.69 | IDO1 (0.38) | IDO1 | |
| SCHEMBL4772123 | 0.69 | LTK (0.35) | — | |
| SCHEMBL4772116 | 0.61 | — | — | |
| SCHEMBL182502 | 0.61 | — | — | |
| SCHEMBL16579833 | 0.58 | TYR (0.33) | IDO1 | |
| SCHEMBL24377676 | 0.58 | — | — | |
| SCHEMBL16830834 | 0.57 | CRBN (0.31) | — | |
| SCHEMBL18250040 | 0.57 | MAOA (0.39) | IDO1 | |
| SCHEMBL15468004 | 0.55 | MAP2K1 (0.60) | — | |
| SCHEMBL21305081 | 0.54 | DYRK1A (0.40) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032694-A1 | AMINO SUBSTITUTED PYRIMIDINE, PYROLLOPYRIDINE AND PYRAZOLOPYRIMIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS AND IN TREATING PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | DANA FARBER CANCER INSTITUTE (US) | 2009-03-12 | — | — | WO | disclosed |