Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | BMX | P51813 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953323 | 0.83 | BTK (0.51) | BTKKITSRCFLT3ITK | |
| SCHEMBL3967674 | 0.82 | BTK (0.53) | BTKKITSRCFLT3ITK | |
| SCHEMBL3965808 | 0.82 | PIK3CB (0.37) | PDCD1CD274 | |
| SCHEMBL1038359 | 0.81 | BTK (0.59) | BTKKITSRCFLT3ITK | |
| SCHEMBL1041847 | 0.80 | BTK (0.52) | BTKSRCFLT3ITKBMX | |
| SCHEMBL1038537 | 0.80 | BTK (0.56) | BTKSRCFLT3ITKBMX | |
| SCHEMBL1042043 | 0.80 | BTK (0.66) | BTK | |
| SCHEMBL3957050 | 0.79 | BTK (0.55) | BTKSRCFLT3ITKBMX | |
| SCHEMBL3960170 | 0.79 | BTK (0.56) | BTKKITSRCFLT3ITK | |
| SCHEMBL3961204 | 0.79 | BTK (0.52) | BTKSRCFLT3ITKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079726-A2 | SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008033857-A2 | SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI PHARMACEUTICALS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |