Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958771 | 0.89 | PDCD1 (0.38) | APPPDCD1CD274CNR2IKBKB | |
| SCHEMBL3961706 | 0.89 | APP (0.39) | APPPDCD1CD274CNR2IKBKB | |
| SCHEMBL1201623 | 0.83 | APP (0.44) | APPPDCD1CD274CNR2IKBKB | |
| SCHEMBL3958453 | 0.82 | APP (0.45) | APPPDCD1CD274CNR2IKBKB | |
| SCHEMBL1202343 | 0.79 | APP (0.49) | APPCNR2KMOCNR1 | |
| SCHEMBL3961710 | 0.77 | APP (0.46) | APPPDCD1CD274CNR2IKBKB | |
| SCHEMBL1201792 | 0.76 | AKR1C3 (0.40) | APPFFAR1 | |
| SCHEMBL1202689 | 0.76 | APP (0.47) | APPCNR2KMOKCNH2 | |
| SCHEMBL1202952 | 0.76 | APP (0.45) | APPCNR2IKBKBCHUKKMO | |
| SCHEMBL1202425 | 0.75 | APP (0.41) | APPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036428-A2 | 1,3,4-TRISUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |