Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958771 | 0.89 | PDCD1 (0.38) | APPIKBKBCHUKPDCD1CD274 | |
| SCHEMBL3958456 | 0.89 | APP (0.43) | APPIKBKBCHUKPDCD1CD274 | |
| SCHEMBL1201623 | 0.83 | APP (0.44) | APPIKBKBCHUKPDCD1CD274 | |
| SCHEMBL3961703 | 0.82 | APP (0.41) | APPIKBKBCHUKFFAR4PDCD1 | |
| SCHEMBL1202689 | 0.79 | APP (0.47) | APPFFAR4ACACBPTGS2PTGS1 | |
| SCHEMBL1202425 | 0.79 | APP (0.41) | APPACACBPTGS2AKR1C4CHRM3 | |
| SCHEMBL8031372 | 0.78 | APP (0.49) | APPFFAR4DHODHACACBAKR1C3 | |
| SCHEMBL3961710 | 0.77 | APP (0.46) | APPIKBKBCHUKPDCD1CD274 | |
| SCHEMBL15494189 | 0.76 | APP (0.47) | APPFFAR4DHODHACACBPTGS2 | |
| SCHEMBL1201792 | 0.76 | AKR1C3 (0.40) | APPACACBPTGS2CHRM3AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036428-A2 | 1,3,4-TRISUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |