Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288928 | 0.81 | MEP1B (0.56) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL288927 | 0.81 | MEP1B (0.56) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3958947 | 0.80 | ANPEP (0.62) | MEN1KMT2AALDH1A1ANPEPHTT | |
| SCHEMBL3958949 | 0.80 | ANPEP (0.62) | MEN1KMT2AALDH1A1ANPEPHTT | |
| SCHEMBL29213358 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1ANPEPHTT | |
| SCHEMBL2248276 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30903297 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1ANPEPHTT | |
| SCHEMBL29213363 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1ANPEPHTT | |
| SCHEMBL6136375 | 0.76 | USP2 (0.56) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL25454651 | 0.76 | MME (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035553-A2 | ANALOGS OF TETRAMIC ACID | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2009-03-19 | — | — | WO | disclosed |