Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12630 | 0.85 | — | — | |
| SCHEMBL12304010 | 0.77 | CNR2 (0.34) | KCNH2AKT1PIK3CAMTOR | |
| SCHEMBL12993553 | 0.76 | — | — | |
| SCHEMBL4742018 | 0.74 | AKT1 (0.33) | KCNH2AKT1PIK3CAMTOR | |
| SCHEMBL4940256 | 0.74 | KCNH2 (0.34) | KCNH2AKT1PIK3CAMTOR | |
| SCHEMBL28184251 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL23812619 | 0.73 | CYP1A2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL20502624 | 0.73 | AKT1 (0.33) | KCNH2AKT1PIK3CAMTOR | |
| SCHEMBL28459300 | 0.73 | CYP1A2 (0.38) | — | |
| SCHEMBL27694260 | 0.73 | CYP1A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079756-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | Cara Therapeutics, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008060552-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | CARA THERAPEUTICS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |