Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 7/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635235 | 0.86 | CNR2 (0.59) | CNR2CNR1EPHX2ABCC9ABCC8 | |
| SCHEMBL1464417 | 0.86 | CNR2 (0.59) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL1463718 | 0.84 | CNR2 (0.58) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL1465731 | 0.83 | CNR2 (0.63) | CNR2CNR1EPHX2ABCC9ABCC8 | |
| SCHEMBL1464572 | 0.73 | NPC1 (0.56) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL1464914 | 0.71 | CYP1A2 (0.61) | CNR2CNR1SMN1; SMN2NAMPT | |
| SCHEMBL1464878 | 0.70 | CNR2 (0.64) | CNR2CNR1ABCC9ABCC8KCNJ11 | |
| SCHEMBL6285653 | 0.68 | RAB9A (0.63) | SMN1; SMN2NAMPT | |
| SCHEMBL1465154 | 0.67 | CNR2 (0.57) | CNR2CNR1ABCC9ABCC8KCNJ11 | |
| SCHEMBL1464505 | 0.67 | CNR2 (0.70) | CNR2CNR1EPHX2ABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |