⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12513402 | 1.00 | — | — | |
| SCHEMBL464469 | 1.00 | — | — | |
| SCHEMBL464411 | 1.00 | — | — | |
| SCHEMBL13037517 | 0.98 | NOS2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL31491221 | 0.98 | NOS2 (0.40) | — | |
| SCHEMBL19415048 | 0.98 | NOS2 (0.40) | — | |
| SCHEMBL5696888 | 0.93 | — | — | |
| SCHEMBL805293 | 0.93 | — | — | |
| SCHEMBL809387 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL933987 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | disclosed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | disclosed |