SCHEMBL3959488

SCHEMBL3959488

N#Cc1[nH]nnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1457382 0.72
SCHEMBL2066913 0.70
SCHEMBL5276473 0.70
SCHEMBL5276905 0.70
SCHEMBL5279693 0.70
SCHEMBL5278849 0.67
SCHEMBL1250411 0.66 ALDH1A1 (0.36)
SCHEMBL1250229 0.66 ERBB2 (0.47)
SCHEMBL18005934 0.65 NPC1 (0.42)
SCHEMBL5286846 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11008416-B2 Aqueous, curable composition, comprising dispersed uretdione prepolymer, reactant and azolate COVESTRO LLC (US) 2021-05-18 US disclosed
US-20210017322-A1 URETDIONE-CONTAINING POLYURETHANE-DISPERSIONS COMPRISING HYDROPHILIC GROUPS COVESTRO DEUTSCHLAND AG (DE) 2021-01-21 US disclosed
CN-111886271-A Aqueous curable compositions comprising dispersed uretdione prepolymers, reactants, and azoles 科思创有限公司 2020-11-03 CN disclosed
CN-111868131-A Uretdione-containing polyurethane dispersions containing hydrophilic groups 科思创德国股份有限公司 2020-10-30 CN disclosed
US-20190292299-A1 AQUEOUS, CURABLE COMPOSITION, COMPRISING DISPERSED URETDIONE PREPOLYMER, REACTANT AND AZOLATE COVESTRO LLC 2019-09-26 US disclosed
EP-3543269-A1 URETDIONE-CONTAINING POLYURETHANE-DISPERSIONS COMPRISING HYDROPHILIC GROUPS Covestro Deutschland AG (DE) 2019-09-25 EP disclosed
EP-1389221-B1 METHOD FOR PRODUCING ALIPHATIC POLYISOCYANATES HAVING AN URETDIONE, ISOCYANURATE AND IMINOOXADIAZINDIONE STRUCTURE BAYER MATERIALSCIENCE AG (DE) 2009-07-22 EP disclosed
EP-1389223-B1 METHOD FOR PRODUCING POLYISOCYANATES BAYER MATERIALSCIENCE AG (DE) 2008-07-23 EP disclosed
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed
US-7030266-B2 Method for producing polyisocyanates BAYER AKTIENGESELLSCHAFT (DE) 2006-04-18 US disclosed
EP-1389221-A1 METHOD FOR PRODUCING ALIPHATIC POLYISOCYANATES HAVING AN URETDIONE, ISOCYANURATE AND IMINOOXADIAZINDIONE STRUCTURE Bayer Aktiengesellschaft (DE) 2004-02-18 EP disclosed
EP-1389223-A1 METHOD FOR PRODUCING POLYISOCYANATES Bayer Aktiengesellschaft (DE) 2004-02-18 EP disclosed
US-6590098-B2 Reacting isocyanates-2+ such as hexamethylene diisocyanate in the presence of catalysts, to form dimers, trimers and/or adducts used as polyurethane paints and coatings BAYER AKTIENGESELLSCHAFT (DE) 2003-07-08 US disclosed
US-20030078361-A1 Method of preparing aliphatic polyisocyanates with uretdione, isocyanurate and iminooxadiazindione structures BAYER AKTIENGESELLSCHAFT (DE) 2003-04-24 US disclosed
US-20030078450-A1 Method for producing polyisocyanates COVESTRO DEUTSCHLAND AG (DE) 2003-04-24 US disclosed
WO-2002092658-A1 METHOD FOR PRODUCING POLYISOCYANATES BAYER AKTIENGESELLSCHAFT (DE) 2002-11-21 WO disclosed
WO-2002092656-A1 METHOD FOR PRODUCING ALIPHATIC POLYISOCYANATES HAVING AN URETDIONE, ISOCYANURATE AND IMINOOXADIAZINDIONE STRUCTURE BAYER AKTIENGESELLSCHAFT (DE) 2002-11-21 WO disclosed