Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535281 | 0.88 | SMPD1 (0.54) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL10861035 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL3960997 | 0.82 | TSHR (0.50) | SMN1; SMN2NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL11284264 | 0.80 | SMPD1 (0.71) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL10861040 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL11286951 | 0.78 | NPC1 (0.78) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL3245222 | 0.77 | SMPD1 (0.67) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL3123036 | 0.77 | MAOB (0.64) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL9434911 | 0.77 | NPC1 (0.56) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 | |
| SCHEMBL3960907 | 0.76 | KMT2A (0.62) | SMN1; SMN2NPC1HPGDRAB9ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| EP-1115738-A4 | SYNTHESIS OF CYCLIC PEPTIDES | UNIV QUEENSLAND (AU) | 2004-09-01 | — | — | EP | disclosed |
| EP-1115738-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018790-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2000-04-06 | — | — | WO | disclosed |