Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286951 | 0.94 | NPC1 (0.78) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL2188210 | 0.91 | SMPD1 (0.76) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL10861035 | 0.91 | SMN1; SMN2 (0.63) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL873776 | 0.90 | SMPD1 (0.70) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL29375753 | 0.88 | SMPD1 (0.75) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL1029034 | 0.88 | SMPD1 (0.75) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL10861040 | 0.88 | SMN1; SMN2 (0.60) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL8843713 | 0.87 | SMN1; SMN2 (0.90) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6586504 | 0.87 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL11271923 | 0.87 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352792-A | 3-Alkoxyflavone antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 1982-10-05 | — | — | US | disclosed |