Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.61 |
| ▸ | MMP14 | P50281 | 11/20 | 0.61 |
| ▸ | MMP12 | P39900 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962546 | 0.89 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL74255 | 0.81 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL88026 | 0.81 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL74550 | 0.79 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL74593 | 0.78 | MMP13 (0.78) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL3960421 | 0.78 | MMP13 (0.49) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL74232 | 0.78 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL76108 | 0.78 | MMP13 (0.71) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL74331 | 0.78 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL3962544 | 0.78 | MMP13 (0.50) | MMP13MMP14MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828166-B1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-07-22 | — | — | EP | claimed |