Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760095 | 0.87 | PPARA (0.46) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL3760093 | 0.87 | PPARA (0.46) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL3763466 | 0.87 | PPARA (0.47) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL3964743 | 0.84 | PPARA (0.38) | PPARAPPARG | |
| SCHEMBL3763317 | 0.83 | PPARA (0.41) | PPARAPPARG | |
| SCHEMBL3959974 | 0.83 | TBXAS1 (0.41) | LMNASMN1; SMN2HTTPPARAPPARG | |
| SCHEMBL3758770 | 0.82 | PPARA (0.42) | SMN1; SMN2PPARAPPARGALDH1A1 | |
| SCHEMBL3769108 | 0.81 | NPC1 (0.41) | NPC1RAB9APPARAPPARGALDH1A1 | |
| SCHEMBL3764480 | 0.81 | PPARA (0.46) | PPARAPPARG | |
| SCHEMBL3758105 | 0.81 | PPARA (0.38) | NPC1RAB9APPARAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |