Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963551 | 0.95 | CNR2 (0.47) | MAPTCNR2CNR1XBP1NPSR1 | |
| SCHEMBL3969890 | 0.91 | CNR2 (0.47) | MAPTCNR2CNR1XBP1NPSR1 | |
| SCHEMBL1464791 | 0.87 | MAPT (0.63) | MAPTCNR2XBP1NPSR1POLB | |
| SCHEMBL3965012 | 0.85 | MAPT (0.50) | MAPTCNR2CNR1XBP1NPSR1 | |
| SCHEMBL1465154 | 0.84 | CNR2 (0.57) | CNR2CNR1POLBRAB9ANPC1 | |
| SCHEMBL1465718 | 0.82 | CNR2 (0.49) | MAPTCNR2CNR1XBP1NPSR1 | |
| SCHEMBL1464708 | 0.81 | CNR2 (0.58) | MAPTCNR2XBP1NPSR1POLB | |
| SCHEMBL1464594 | 0.81 | CNR2 (0.57) | CNR2CNR1CCR6RAB9ANPC1 | |
| SCHEMBL1463920 | 0.79 | CNR2 (0.56) | MAPTCNR2XBP1NPSR1POLB | |
| SCHEMBL1464878 | 0.79 | CNR2 (0.64) | CNR2CNR1CCR6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |