Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 3/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969890 | 0.90 | CNR2 (0.47) | MAPTCNR2POLBPHGDHXBP1 | |
| SCHEMBL3962721 | 0.88 | CNR2 (0.62) | MAPTCNR2GRM5CNR1LMNA | |
| SCHEMBL1464791 | 0.88 | MAPT (0.63) | MAPTCNR2POLBPHGDHXBP1 | |
| SCHEMBL3961312 | 0.85 | MAPT (0.48) | MAPTCNR2POLBPHGDHXBP1 | |
| SCHEMBL1464708 | 0.84 | CNR2 (0.58) | MAPTCNR2POLBPHGDHXBP1 | |
| SCHEMBL1464304 | 0.84 | CNR2 (0.50) | CNR2GRM5CNR1 | |
| SCHEMBL3969896 | 0.82 | CNR2 (0.61) | MAPTCNR2PHGDHGRM5CNR1 | |
| SCHEMBL1465718 | 0.82 | CNR2 (0.49) | MAPTCNR2POLBPHGDHXBP1 | |
| SCHEMBL1464507 | 0.81 | TAS2R14 (0.52) | CNR2GRM5CNR1 | |
| SCHEMBL3963551 | 0.81 | CNR2 (0.47) | MAPTCNR2POLBXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |