Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961000 | 0.90 | PPARA (0.44) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3964738 | 0.89 | PPARA (0.51) | PPARAPPARGGPR119L3MBTL1PKM | |
| SCHEMBL3759907 | 0.88 | PPARA (0.50) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3759904 | 0.88 | PPARA (0.50) | PPARAPPARGL3MBTL1 | |
| SCHEMBL3763268 | 0.85 | PPARA (0.45) | PPARAPPARGGPR119L3MBTL1PKM | |
| SCHEMBL3956249 | 0.82 | GPR119 (0.41) | PPARAPPARGGPR119 | |
| SCHEMBL3961712 | 0.82 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL3957381 | 0.80 | PPARA (0.45) | PPARAPPARGGPR119 | |
| SCHEMBL3961687 | 0.79 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL3958880 | 0.79 | PPARA (0.39) | PPARAPPARGGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |