Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.75 |
| ▸ | ADRA2B | P18089 | 17/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 17/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 16/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9654915 | 0.85 | NISCH (0.77) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| SCHEMBL3961615 | 0.83 | NISCH (0.52) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| SCHEMBL10035176 | 0.81 | ADRA2A (1.00) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| SCHEMBL546178 | 0.81 | NISCH (0.50) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| SCHEMBL3961636 | 0.81 | NISCH (0.50) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| SCHEMBL10978713 | 0.78 | NISCH (0.67) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| Levlofexidine SCHEMBL947241 | 0.77 | ADRA2A (1.00) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| Lofexidine SCHEMBL48960 | 0.77 | ADRA2A (1.00) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| Dexlofexidine SCHEMBL124602 | 0.77 | ADRA2A (1.00) | NISCHADRA2BADRA2CADRA2AHTR1A | |
| Hydrochloric Acid SCHEMBL10982604 | 0.76 | NISCH (0.64) | NISCHADRA2BADRA2CADRA2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036908-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-26 | — | — | WO | disclosed |