Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.42 |
| ▸ | PPARG | P37231 | 13/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962122 | 0.90 | PPARA (0.50) | PPARAPPARGL3MBTL1LMNA | |
| SCHEMBL3764453 | 0.88 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL3764450 | 0.88 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL3959581 | 0.88 | PPARA (0.49) | PPARAPPARG | |
| SCHEMBL3959542 | 0.87 | PPARA (0.53) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL3956558 | 0.87 | PPARA (0.53) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL3761964 | 0.84 | PPARA (0.41) | PPARAPPARGL3MBTL1HDAC3HDAC4 | |
| SCHEMBL3962164 | 0.84 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL3961687 | 0.84 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL3961695 | 0.84 | PPARA (0.41) | PPARAPPARGRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |