Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.41 |
| ▸ | PPARG | P37231 | 12/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959581 | 0.92 | PPARA (0.49) | PPARAPPARGGPR119 | |
| SCHEMBL3962122 | 0.91 | PPARA (0.50) | PPARAPPARG | |
| SCHEMBL3964664 | 0.91 | PPARA (0.50) | PPARAPPARGGPR119 | |
| SCHEMBL3960953 | 0.91 | PSEN1 (0.43) | PPARAPPARGNPC1RAB9A | |
| SCHEMBL3964738 | 0.90 | PPARA (0.51) | PPARAPPARGGPR119 | |
| SCHEMBL3958880 | 0.90 | PPARA (0.39) | PPARAPPARGGPR119 | |
| SCHEMBL3962164 | 0.90 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL4183103 | 0.89 | PPARA (0.39) | PPARAPPARGGPR119 | |
| SCHEMBL3959737 | 0.88 | PPARA (0.40) | PPARAPPARG | |
| SCHEMBL3956249 | 0.88 | GPR119 (0.41) | PPARAPPARGGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989192-B1 | 1,3-DIOXANE CARBOXYLIC ACIDS | CADILA HEALTHCARE LTD (IN) | 2009-07-22 | — | — | EP | claimed |