SCHEMBL396163

SCHEMBL396163

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)NC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
MMP1 P03956 2/20 0.32
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
MMP8 P22894 2/20 0.32
MMP13 P45452 2/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396442 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL345870 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL396425 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL394930 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL397047 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL6287445 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL392843 0.96 LMNA (0.50) LMNACA1CA2MMP1MMP2
SCHEMBL5943550 0.88 LMNA (0.39) LMNA
SCHEMBL6283534 0.74
SCHEMBL1509092 0.74 LMNA (0.35) LMNACA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230414716-A1 SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS EMULSIONS REGENERON PHARMACEUTICALS, INC. 2023-12-28 US claimed
CN-116940347-A Sustained release formulations emulsified using non-aqueous films 里珍纳龙药品有限公司 2023-10-24 CN claimed
EP-4251128-A1 SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS MEMBRANE EMULSIFICATION Regeneron Pharmaceuticals, Inc. (US) 2023-10-04 EP claimed
EP-4065086-A1 SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS EMULSIONS REGENERON PHARMACEUTICALS, INC. (US) 2022-10-05 EP claimed
CN-114760986-A Sustained release formulations using non-aqueous emulsions 里珍纳龙药品有限公司 2022-07-15 CN claimed
WO-2022115588-A1 SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS MEMBRANE EMULSIFICATION REGENERON PHARMACEUTICALS, INC. (US) 2022-06-02 WO claimed
US-20050003977-A1 Composition for cleaning DAIKIN INDUSTRIES, LTD. (JP) 2005-01-06 US claimed
EP-1447440-A1 COMPOSITION FOR CLEANING Daikin Industries, Ltd. (JP) 2004-08-18 EP claimed
EP-0091313-B1 PERFLUOROHYDROCARBONS AS VEHICLES FOR ADMINISTERING DRUGS ALCON LABORATORIES, INC. (US) 1990-09-05 EP claimed
US-8871885-B2 Ethylene-a-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-28 US disclosed
US-8809462-B2 Ethylene-α-olefin copolymer, molded article, catalyst for copolymerization, and method for producing an ethylene-α-olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-20140017687-A1 METHOD FOR PERFORMING MOLECULAR REACTIONS BY USING IMMISCIBLE INTERMEDIATE FLUIDS KONINKLIJKE PHILIPS N.V. (NL) 2014-01-16 US disclosed
EP-1860141-B1 Process for the surface modification of a polymer substrate and polymers formed therefrom AMO UPPSALA AB (SE) 2013-12-25 EP disclosed
US-8501891-B2 Ethylene-α-olefin copolymer and molded article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-06 US disclosed
EP-0889067-A1 Amorphous HFP/TFE copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-07 EP disclosed
EP-0808335-A2 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-26 EP disclosed
US-5663255-A POLYMERS FOR COATINGS, FILMS AND ENCAPSULATION WITH LOW COST POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-02 US disclosed
US-5637663-A RADICAL INITIATING A CONTINUOUS COPOLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-06-10 US disclosed
WO-1996024624-A2 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-15 WO disclosed
US-5478905-A Reacting tetrafluoroethylene and hexafluoropropylene in the presence of a radical initiator E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414716-A1 SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS EMULSIONS FIBP, NPFFR1, VEGFA LMNA 3871/4885CA1 3275/4885CA2 4356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.