Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.80 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HTR5A | P47898 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967420 | 0.89 | HTR6 (0.76) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL3964605 | 0.89 | HTR6 (0.79) | HTR6HTR7HTR5A | |
| SCHEMBL3155934 | 0.89 | HTR6 (0.82) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL3147543 | 0.89 | HTR6 (1.00) | HTR6HTR7HTR5A | |
| SCHEMBL3959134 | 0.87 | HTR6 (0.76) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL3957586 | 0.86 | HTR6 (0.77) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL3965872 | 0.85 | HTR6 (0.75) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL3961658 | 0.83 | HTR6 (0.73) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL1576280 | 0.83 | HTR6 (0.70) | HTR6HTR7HTR5AHTR1AHTR2A | |
| SCHEMBL1576109 | 0.83 | HTR6 (0.85) | HTR6HTR7HTR5AHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | claimed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | claimed |
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |