Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.76 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HTR5A | P47898 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957568 | 0.97 | HTR6 (0.75) | HTR6HTR7HTR5ASLC6A4 | |
| SCHEMBL3148443 | 0.91 | HTR6 (0.82) | HTR6HTR7HTR5A | |
| SCHEMBL3958843 | 0.89 | HTR6 (0.69) | HTR6HTR7HTR5A | |
| SCHEMBL3958067 | 0.87 | HTR6 (0.67) | HTR6HTR7HTR5ASLC6A4 | |
| SCHEMBL1423485 | 0.87 | HTR6 (1.00) | HTR6HTR7HTR5A | |
| SCHEMBL3960589 | 0.86 | HTR6 (0.68) | HTR6HTR7HTR5ASLC6A4 | |
| SCHEMBL13588646 | 0.83 | HTR6 (0.81) | HTR6HTR7HTR5A | |
| SCHEMBL1576283 | 0.83 | HTR6 (0.69) | HTR6HTR7HTR5A | |
| SCHEMBL3148768 | 0.82 | HTR6 (1.00) | HTR6HTR7HTR5A | |
| SCHEMBL4967568 | 0.81 | HTR6 (0.70) | HTR6HTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | claimed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | claimed |
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |