Phenaphthazine

Phenaphthazine

SCHEMBL3962052

O=[N+]([O-])c1ccc(/N=N/c2c(S(=O)(=O)O)cc3cc(S(=O)(=O)O)ccc3c2O)c([N+](=O)[O-])c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 4/20 0.53
▸ CYP2C9 P11712 2/20 0.53
▸ HPGD P15428 2/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ ALOX12 P18054 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ CSNK2A1 P68400 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ CD40 P25942 1/20 0.52
▸ CD40LG P29965 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ ALDH1A1 P00352 2/20 0.51
▸ HIF1A Q16665 2/20 0.51
▸ ENPP2 Q13822 8/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenaphthazine SCHEMBL8380113 1.00 CYP1A2 (0.53) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
Phenaphthazine SCHEMBL1554804 1.00 CYP1A2 (0.53) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
Phenaphthazine SCHEMBL8380111 0.99 CYP1A2 (0.52) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
SCHEMBL10819296 0.90 ALDH1A1 (0.52) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
SCHEMBL17089143 0.90 CD40 (0.50) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
SCHEMBL18775373 0.88 CYP1A2 (0.52) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
SCHEMBL10595355 0.88 TDP1 (0.45) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
Phenaphthazine SCHEMBL155287 0.87 APEX1 (0.55) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
Phenaphthazine SCHEMBL8380112 0.87 APEX1 (0.55) CYP1A2CYP2C9HPGDCYP3A4CYP2D6
Phenaphthazine SCHEMBL29446756 0.87 APEX1 (0.55) CYP1A2CYP2C9HPGDCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2904385-B1 INDICATOR DEVICE INSIGNIA TECH LTD (GB) 2023-11-29 — — EP claimed
US-11371974-B2 Indicator device INSIGNIA TECHNOLOGIES LIMITED (GB) 2022-06-28 — — US claimed
US-20190137463-A1 INDICATOR DEVICE INSIGNIA TECHNOLOGIES LIMITED (GB) 2019-05-09 — — US claimed
EP-3469353-A1 INDICATOR DEVICE Insignia Technologies Limited (GB) 2019-04-17 — — EP claimed
WO-2017216542-A1 INDICATOR DEVICE INSIGNIA TECHNOLOGIES LIMITED (GB) 2017-12-21 — — WO claimed
EP-2904385-A1 INDICATOR DEVICE Insignia Technologies Ltd. (GB) 2015-08-12 — — EP claimed
WO-2014132065-A1 TIME PASSAGE INDICATOR INSIGNIA TECHNOLOGIES LTD (GB) 2014-09-04 — — WO claimed
WO-2014053846-A1 INDICATOR DEVICE INSIGNIA TECHNOLOGIES LTD (GB) 2014-04-10 — — WO claimed
US-5989840-A IMMUNOASSAY CHAMBER WITH IMMOBILIZED ANTIGEN; SUPPORT WITH INDICATOR FOR PRESENCE OF AMMONIA CONSTITUENT; COLORIMETRIC ANALYSIS AMERICARE INTERNATIONAL DIAGNOSTICS, INC. (US) 1999-11-23 — — US claimed
EP-2904385-B1 INDICATOR DEVICE INSIGNIA TECH LTD (GB) 2023-11-29 — — EP disclosed
US-20230127982-A1 INDICATOR FILM INSIGNIA TECHNOLOGIES LTD (GB) 2023-04-27 — — US disclosed
EP-4121757-A1 INDICATOR FILM Insignia Technologies Limited (GB) 2023-01-25 — — EP disclosed
US-11371974-B2 Indicator device INSIGNIA TECHNOLOGIES LIMITED (GB) 2022-06-28 — — US disclosed
WO-2021186175-A1 INDICATOR FILM INSIGNIA TECHNOLOGIES LTD (GB) 2021-09-23 — — WO disclosed
US-20050143505-A1 Paint with color change additive and method of application and painted substrate PPG ARCHITECTURAL FINISHES, INC. 2005-06-30 — — US disclosed
US-6894095-B2 Color-changing wallpaper adhesive primer/activator THE DIAL CORPORATION (US) 2005-05-17 — — US disclosed
US-20040012622-A1 Color-changing wallpaper adhesive primer/activator ROMAN PRODUCTS, LLC 2004-01-22 — — US disclosed
US-20040014875-A1 Color-changing wallpaper adhesive primer/activator ROMAN DECORATING PRODUCTS 2004-01-22 — — US disclosed
US-6589761-B1 In food using a three layer composite consisting of a transparent base, an indicator exhibiting color change when exposed to changes in pH, and a gas permeable cover; carbon dioxide production leads to color change FREADMAN MARV (US) 2003-07-08 — — US disclosed
WO-1999025189-A1 AGRICULTURAL COMPOSITIONS COMPRISING A PH INDICATOR GOUWS & SCHEEPERS PTY. LIMITED (ZA) 1999-05-27 — — WO disclosed
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