SCHEMBL396206

SCHEMBL396206

Nc1cccc2nsnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
KDM4E B2RXH2 4/20 1.00
HSD17B10 Q99714 3/20 1.00
HIF1A Q16665 1/20 1.00
TXNRD1 Q16881 1/20 0.48
TXNRD3 Q86VQ6 1/20 0.48
TXNRD2 Q9NNW7 1/20 0.48
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
ALDH1A1 P00352 7/20 0.44
POLB P06746 2/20 0.44
HPGD P15428 2/20 0.42
CASP1 P29466 1/20 0.42
PTPN11 Q06124 3/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
DUSP3 P51452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23055877 0.82 MAPT (0.69) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL31756355 0.77 MAPT (0.62) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL198065 0.76 MAPT (0.61) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL5513976 0.75 MAPT (0.58) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL3632810 0.73 MAPT (0.57) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL1172929 0.73 MAPT (0.57) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL1913612 0.73 MAPT (0.64) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL762283 0.73 MAPT (0.57) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL10843606 0.73 KDM4E (0.57) MAPTKDM4EHSD17B10HIF1ATXNRD1
SCHEMBL1821199 0.73 MAPT (0.57) MAPTKDM4EHSD17B10HIF1ATXNRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212682-A1 FILM, PREPARATION METHOD THEREOF AND PHOTOELECTRIC DEVICE TCL TECHNOLOGY GROUP CORPORATION (CN) 2025-06-26 US claimed
CN-119264127-A Tizanidine intermediate impurity, preparation method and intermediate detection method 湖南方盛制药股份有限公司 2025-01-07 CN claimed
WO-2024035207-A1 ANTI-CORROSIVE CAPSULE, MANUFACTURING METHOD THEREFOR, BRAKE PAD, AND MANUFACTURING METHOD THEREFOR 성균관대학교산학협력단 2024-02-15 WO claimed
WO-2023204651-A1 BRAKE PAD COMPRISING ANTI-CORROSION ADDITIVE AND METHOD FOR MANUFACTURING SAME 성균관대학교산학협력단 2023-10-26 WO claimed
WO-2023135609-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT SOLVENT-FREE ORGANIC LIQUID COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-07-20 WO claimed
CN-114740694-A Photoresist stripping liquid and preparation method thereof 芯越微电子材料(嘉兴)有限公司 2022-07-12 CN claimed
CN-113248456-B Preparation and application of double pH-responsive aggregation-induced red light emitting material 北京科技大学 2022-05-31 CN claimed
CN-113209828-B Antibacterial ultrafiltration membrane and preparation method thereof 山东超滤环境科技有限公司 2022-05-06 CN claimed
CN-113248456-A Preparation and application of aggregation-induced red light emitting material with dual pH responses 北京科技大学 2021-08-13 CN claimed
CN-113209828-A Antibacterial ultrafiltration membrane and preparation method thereof 山东超滤环境科技有限公司 2021-08-06 CN claimed
US-20090246666-A1 THIADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
US-20060222997-A1 Adhesion improver for photosensitive resin composition and photosensitive resin composition containing same KOBAYASHI SATOSHI 2006-10-05 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
US-4810397-A ALUMINUM COMPOUND, ACID, THIADIAZOLE OR TRIAZOLE UNION OIL COMPANY OF CALIFORNIA (US) 1989-03-07 US claimed
US-4719001-A ALUMINUM COMPOUND AND THIADIAZOLE DERIVATIVE UNION OIL COMPANY OF CALIFORNIA (US) 1988-01-12 US claimed