Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.48 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.48 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198065 | 0.76 | MAPT (0.61) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL246997 | 0.75 | MAPT (0.44) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL396206 | 0.73 | MAPT (1.00) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL10843606 | 0.73 | KDM4E (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL1821199 | 0.73 | MAPT (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL3632810 | 0.73 | MAPT (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL1172929 | 0.73 | MAPT (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL762283 | 0.73 | MAPT (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL13836503 | 0.73 | MAPT (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 | |
| SCHEMBL3424124 | 0.73 | KDM4E (0.57) | MAPTKDM4EHSD17B10HIF1ATXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534535-B | Strong conjugated organic small molecular material and preparation method and application thereof | 齐鲁工业大学(山东省科学院) | 2025-03-14 | — | — | CN | claimed |
| CN-116041343-B | Organic magnetic material and preparation method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-117534535-A | Strong conjugated organic small molecular material and preparation method and application thereof | 齐鲁工业大学(山东省科学院) | 2024-02-09 | — | — | CN | claimed |
| CN-116041343-A | Organic magnetic material and preparation method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2023-05-02 | — | — | CN | claimed |
| US-12583870-B2 | Azaheteroaryl compound and application thereof | SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) | 2026-03-24 | — | — | US | disclosed |
| US-20260049074-A1 | THIADIAZOLYL DERIVATIVES | IDEAYA BIOSCIENCES, INC. (US) | 2026-02-19 | — | — | US | disclosed |
| US-12509454-B2 | Thiadiazolyl derivatives | IDEAYA BIOSCIENCES, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-12404280-B2 | Heterocyclic compound, and organic light-emitting element using same | LT MATERIALS CO., LTD. (KR) | 2025-09-02 | — | — | US | disclosed |
| US-20250270215-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-08-28 | — | — | US | disclosed |
| EP-3701249-B1 | DETECTION METHOD | UNIV QUEENSLAND (AU) | 2025-07-09 | — | — | EP | disclosed |
| US-20250123206-A1 | DETECTION METHOD | UNIV QUEENSLAND (AU) | 2025-04-17 | — | — | US | disclosed |
| CN-117534535-B | Strong conjugated organic small molecular material and preparation method and application thereof | 齐鲁工业大学(山东省科学院) | 2025-03-14 | — | — | CN | disclosed |
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009108838-A1 | BRIDGED, BICYCLIC HETEROCYCLIC OR SPIRO BICYCLIC HETEROCYCLIC DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-03 | — | — | WO | disclosed |
| US-20090221762-A1 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | THE TRUSSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090197889-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2009-08-06 | — | — | US | disclosed |
| CN-101497610-A | Dithiazole ethylene compound containing 2,1,3-diazosulfide unit | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-08-05 | — | — | CN | disclosed |
| WO-2007081991-A9 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | UNIV PENNSYLVANIA (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007081991-A2 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-19 | — | — | WO | disclosed |
| CN-1906704-A | Hole transport layer compositions and related diode devices | UNIV NORTHWESTERN (US) | 2007-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049074-A1 | THIADIAZOLYL DERIVATIVES | POLH, POLM, POLD1 | MAPT 4800/4885KDM4E 3719/4885HSD17B10 440/4885 |
| US-20090221762-A1 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | PML, ILK, PARG | MAPT 83/4885KDM4E 4081/4885HSD17B10 3468/4885 |
| US-12583870-B2 | Azaheteroaryl compound and application thereof | NR3C1, EED, EZH2 | MAPT 4193/4885KDM4E 503/4885HSD17B10 632/4885 |
| US-20090197889-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | MKI67, PCNA, CCNI | MAPT 4618/4885KDM4E 1606/4885HSD17B10 4356/4885 |
| US-12404280-B2 | Heterocyclic compound, and organic light-emitting element using same | CRY1, CYP1A1, CYP1B1 | MAPT 1769/4885KDM4E 2411/4885HSD17B10 1067/4885 |
| US-20250123206-A1 | DETECTION METHOD | OPRK1, OPRM1, SIGMAR1 | MAPT 1302/4885KDM4E 4142/4885HSD17B10 1215/4885 |
| US-12509454-B2 | Thiadiazolyl derivatives | POLD1, POLQ, DNA2 | MAPT 2801/4885KDM4E 3903/4885HSD17B10 617/4885 |
| US-20250270215-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | ALK, TGFBR1, TGFBR2 | MAPT 2205/4885KDM4E 555/4885HSD17B10 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.