⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358647 | 0.97 | — | — | |
| SCHEMBL1569461 | 0.88 | — | — | |
| SCHEMBL563619 | 0.86 | — | — | |
| SCHEMBL16035833 | 0.83 | — | — | |
| SCHEMBL15546403 | 0.75 | — | — | |
| SCHEMBL19358644 | 0.69 | — | — | |
| SCHEMBL6668394 | 0.67 | — | — | |
| SCHEMBL1303719 | 0.67 | — | — | |
| SCHEMBL20291506 | 0.66 | — | — | |
| SCHEMBL21591085 | 0.64 | SIGMAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538123-B2 | Indole derivative having piperidine ring | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070219179-A1 | Indole Derivative Having Piperidine Ring | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1757599-A1 | INDOLE DERIVATIVES HAVING PIPERIDINE RINGS | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-20050256103-A1 | Indole derivative having piperidine ring | EISAI CO., LTD. | 2005-11-17 | — | — | US | disclosed |