Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL14248079 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL17141374 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL16720928 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL2856303 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL3409 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL59 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL23457363 | 0.76 | — | — | |
| Dimethyl Sulfoxide SCHEMBL11665563 | 0.76 | — | — | |
| Dimethyl Sulfoxide SCHEMBL7933303 | 0.76 | — | — | |
| Dimethyl Sulfoxide SCHEMBL22445325 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078007-A1 | IKK-BETA SERINE-THREONINE PROTEIN KINASE INHIBITORS | Chroma Therapeutics Limited (GB) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008053182-A1 | IKK-β SERINE-THREONINE PROTEIN KINASE INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |