Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.58 |
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466012 | 0.87 | CNR2 (0.60) | CNR2CNR1EDNRBEDNRA | |
| SCHEMBL1465811 | 0.85 | CNR2 (0.75) | CNR2CNR1MAPK13MAPTMAPK12 | |
| SCHEMBL12095618 | 0.81 | CNR2 (0.56) | CNR2CNR1MAPK13MAPTMAPK12 | |
| SCHEMBL1464728 | 0.80 | CNR2 (0.68) | CNR2CNR1MAPK13MAPTMAPK12 | |
| SCHEMBL1464570 | 0.75 | CNR2 (0.65) | CNR2CNR1MAPTEDNRBEDNRA | |
| SCHEMBL469410 | 0.75 | CNR2 (1.00) | CNR2CNR1MAPK13MAPTMAPK12 | |
| SCHEMBL1465183 | 0.75 | CNR2 (0.78) | CNR2CNR1MAPK13MAPTMAPK12 | |
| SCHEMBL1464908 | 0.73 | CNR2 (0.63) | CNR2CNR1MAPK14 | |
| SCHEMBL3960202 | 0.71 | CNR2 (0.47) | CNR2CNR1MAPK14 | |
| SCHEMBL3963534 | 0.71 | CNR2 (0.55) | CNR2CNR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |