Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.55 |
| ▸ | CNR1 | P21554 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464457 | 0.97 | CNR2 (0.58) | CNR2CNR1SMN1; SMN2MAPK14 | |
| SCHEMBL1464908 | 0.93 | CNR2 (0.63) | CNR2CNR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12095618 | 0.90 | CNR2 (0.56) | CNR2CNR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1465550 | 0.80 | CNR2 (0.67) | CNR2CNR1ALDH1A1MAPK14 | |
| SCHEMBL1465876 | 0.79 | CNR2 (0.59) | CNR2CNR1MAPK14 | |
| SCHEMBL3962718 | 0.79 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL12095559 | 0.78 | CNR2 (0.60) | CNR2CNR1MAPK14 | |
| SCHEMBL10171346 | 0.78 | CNR2 (0.60) | CNR2CNR1MAPK14 | |
| SCHEMBL1464728 | 0.78 | CNR2 (0.68) | CNR2CNR1LMNAMAPK14 | |
| SCHEMBL13015651 | 0.75 | ALDH1A1 (0.48) | CNR2CNR1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |