Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3181124 | 0.85 | TSHR (0.42) | SIRT2TSHR | |
| SCHEMBL3192661 | 0.85 | TSHR (0.42) | SIRT2TSHR | |
| SCHEMBL3188358 | 0.85 | TSHR (0.42) | SIRT2TSHR | |
| SCHEMBL3963526 | 0.85 | TSHR (0.42) | SIRT2TSHR | |
| SCHEMBL3193317 | 0.83 | TSHR (0.39) | SIRT2TSHR | |
| SCHEMBL11845791 | 0.80 | SIRT2 (0.37) | SIRT2CYP19A1TSHR | |
| SCHEMBL9646862 | 0.80 | TSHR (0.38) | SIRT2TSHRCETP | |
| SCHEMBL11503129 | 0.80 | TSHR (0.38) | SIRT2TSHRCETP | |
| SCHEMBL22098328 | 0.79 | TSHR (0.36) | SIRT2TSHR | |
| SCHEMBL28756563 | 0.79 | TSHR (0.36) | SIRT2TSHRCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542981-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4,5,6,7-TETRAHYDRO-6-AMINOBENZOTHIAZOLES FROM CYCLOHEXANES AND CYCLOHEXANONES AS INTERMEDIATES | GENERICS UK LTD (GB) | 2009-07-22 | — | — | EP | claimed |
| EP-1023273-B1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5HT1A RECEPTORS | PF MEDICAMENT (FR) | 2002-06-05 | — | — | EP | disclosed |
| EP-1023273-A1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5T H1A RECEPTORS | PIERRE FABRE MEDICAMENT (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999020613-A1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5T H1A RECEPTORS | PIERRE FABRE MEDICAMENT (FR) | 1999-04-29 | — | — | WO | disclosed |