Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429214 | 0.86 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1RXFP1KDM4E | |
| SCHEMBL3968959 | 0.85 | MAPT (0.31) | MAPTSMN1; SMN2KMT2ANPBWR1PSEN1 | |
| SCHEMBL3968759 | 0.83 | MAPT (0.33) | MAPTSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL3967776 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1RXFP1KDM4E | |
| SCHEMBL3899668 | 0.81 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1RXFP1KDM4E | |
| SCHEMBL6698768 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1RXFP1KDM4E | |
| SCHEMBL7047790 | 0.74 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1RXFP1KDM4E | |
| SCHEMBL3896596 | 0.71 | KMT2A (0.34) | MAPTSMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL7118784 | 0.71 | KDM4E (0.40) | MAPTSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL30659834 | 0.70 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916658-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-0322926-B2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0322926-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0916658-A1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | Nichols Institute Diagnostics (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5290936-A | Indicators or labels for antibodies or medical diagnosis | LONDON DIAGNOSTICS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5283334-A | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0322926-A2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | LONDON DIAGNOSTICS, INC. (US) | 1989-07-05 | — | — | EP | disclosed |