Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533773 | 0.94 | LMNA (0.38) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL9317254 | 0.86 | KDM4E (0.40) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL31163697 | 0.85 | ACHE (0.32) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL641602 | 0.85 | ACHE (0.32) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL7538135 | 0.85 | PLA2G2A (0.41) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL7532016 | 0.82 | TACR3 (0.36) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL3143334 | 0.82 | KDM4E (0.44) | KDM4ELMNAALDH1A1MAPTPOLB | |
| SCHEMBL10578489 | 0.82 | KMT2A (0.48) | KDM4ELMNAPLA2G1BATG4BHTT | |
| SCHEMBL3092289 | 0.81 | MEN1 (0.52) | KDM4ELMNAHTTALDH1A1MAPT | |
| SCHEMBL30659834 | 0.81 | MAPT (0.40) | KDM4ELMNAPLA2G1BATG4BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298708-B1 | METHOD FOR DETERMINING THYROXINE UPTAKE | Ciba Corning Diagnostics Corp. (US) | 1992-11-11 | — | — | EP | claimed |
| US-4824777-A | Method for determining thyroxine uptake | CIBA CORNING DIAGNOSTICS CORP. (US) | 1989-04-25 | — | — | US | claimed |
| CN-106124777-A | Acridine labelling conjugate and preparation method thereof, chemical luminescence reagent kit | 深圳市亚辉龙生物科技股份有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106053443-A | Acridine marker conjugate and preparation method thereof and chemiluminescent kit | 深圳市亚辉龙生物科技股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| EP-0754178-B1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | BAYER AG (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-0982298-A1 | Novel functionalized hydrophilic acridinium esters | Ciba Corning Diagnostics Corp. (US) | 2000-03-01 | — | — | EP | disclosed |
| US-5656426-A | USEFUL AS CHEMILUMINESCENT AGENT IN IMMUNOASSAY AND GENE PROBE ASSAY WITH IMPROVED SENSITIVITY | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1995027702-A1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-10-19 | — | — | WO | disclosed |
| US-5196349-A | Labeled antibody, thyroxine, triiodothyronine, immobilized, modified by succinylation | CIBA CORNIGN DIAGNOSTICS CORP. (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0298708-B1 | METHOD FOR DETERMINING THYROXINE UPTAKE | Ciba Corning Diagnostics Corp. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0263657-B1 | POLYSUBSTITUTED ARYL ACRIDINIUM ESTERS | Ciba Corning Diagnostics Corp. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5110932-A | Chemiluminescent immunoassay | CIBA CORNING DIAGNOSTICS CORP. (US) | 1992-05-05 | — | — | US | disclosed |
| US-4927769-A | OXIDIZING AN ACRIDINIUM ESTER IN THE PRESENCE OF A CATIONIC SURFACTANT, NONIONIC SURFACTANT OR SULFATED PRIMARY ALCOHOL | CIBA CORNING DIAGNOSTICS CORP. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4918192-A | LUMINESCENCE; LABELS FOR IMMUNOASSAY | CIBA CORNING DIAGNOSTICS CORP. (US) | 1990-04-17 | — | — | US | disclosed |
| US-4824777-A | Method for determining thyroxine uptake | CIBA CORNING DIAGNOSTICS CORP. (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0298708-A2 | Method for determining thyroxine uptake | Ciba Corning Diagnostics Corp. (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4745181-A | STABLE LABELS FOR CHEMILUMINESCENT IMMUNOASSAY | CIBA CORNING DIAGNOSTICS CORP. (US) | 1988-05-17 | — | — | US | disclosed |