Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.74 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.74 |
| ▸ | FABP3 | P05413 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PRKCA | P17252 | 4/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dipalmitin SCHEMBL4326807 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL18114342 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL3803615 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL1422042 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL18114371 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL3654560 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL18114373 | 0.94 | PRKCA (0.68) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Diolein SCHEMBL3652589 | 0.94 | PRKCA (0.68) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| Phosphocholine SCHEMBL18114339 | 0.94 | PRKCA (0.68) | SMN1; SMN2NR5A2NR5A1FABP3MAPT | |
| 1,2-Dipalmitin SCHEMBL17223985 | 0.92 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1FABP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129387-A2 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | WO | claimed |
| WO-2016156330-A1 | SOLID PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS SOFOSBUVIR AND A PHOSPHOLIPID | RATIOPHARM GMBH (DE) | 2016-10-06 | — | — | WO | disclosed |